Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628335 | 1.00 | RARB (0.52) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8628038 | 1.00 | RARB (0.52) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8629086 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8447769 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8623510 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8625744 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8624968 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8626785 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8629141 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8627072 | 0.99 | RARB (0.51) | RARBHPGDSMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759443-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-02 | — | — | US | disclosed |