Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7882303 | 0.99 | AR (0.47) | ARKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL7873563 | 0.91 | AR (0.56) | ARKDM4EALDH1A1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7877804 | 0.90 | AR (0.55) | ARKDM4EALDH1A1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7882110 | 0.88 | AR (0.46) | ARKDM4EALDH1A1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7881242 | 0.87 | KDM4E (0.45) | ARKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL7873301 | 0.85 | PDGFRB (0.45) | ARKDM4EALDH1A1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7880907 | 0.85 | MEN1 (0.54) | KDM4EALDH1A1FLT3MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL7873549 | 0.85 | PDGFRB (0.45) | ARKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL7882001 | 0.80 | KDM4E (0.50) | ARKDM4EALDH1A1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7882186 | 0.80 | KDM4E (0.50) | ARKDM4EALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622356-B1 | Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange | SUMITOMO PHARMA (JP) | 1998-07-01 | — | — | EP | disclosed |
| EP-0622356-A1 | Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-02 | — | — | EP | disclosed |