Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623518 | 0.88 | GAA (0.46) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8624755 | 0.88 | GAA (0.46) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8623924 | 0.80 | GAA (0.51) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8625020 | 0.80 | GAA (0.51) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8623112 | 0.79 | GAA (0.43) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8623108 | 0.79 | GAA (0.43) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8627477 | 0.78 | GAA (0.46) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8627479 | 0.78 | GAA (0.46) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8623967 | 0.78 | GAA (0.44) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8623814 | 0.74 | GAA (0.55) | GAAALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |