Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | GLP1R | P43220 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8633279 | 0.92 | AVPR2 (0.49) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL8629765 | 0.91 | AVPR2 (0.47) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8627338 | 0.91 | AVPR2 (0.47) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL8632071 | 0.90 | AVPR2 (0.46) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL4687939 | 0.87 | AVPR2 (0.60) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8633282 | 0.85 | AVPR2 (0.48) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8634096 | 0.85 | AVPR2 (0.48) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8630871 | 0.84 | AVPR2 (0.44) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL8634086 | 0.83 | AVPR2 (0.43) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8632049 | 0.82 | AVPR2 (0.63) | AVPR2AVPR1AABCB11ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | claimed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |