Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829632 | 0.88 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL7842088 | 0.82 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL7839624 | 0.78 | KMT2A (0.48) | EDNRAEDNRB | |
| SCHEMBL8037809 | 0.77 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL7840661 | 0.76 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL7842077 | 0.75 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL8147810 | 0.75 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL7839726 | 0.74 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7841623 | 0.72 | KMT2A (0.44) | EDNRA | |
| SCHEMBL7842300 | 0.72 | EDNRA (0.57) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882030-A1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK PATENT GmbH (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997030982-A1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-08-28 | — | — | WO | disclosed |