Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7881092 | 0.99 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8628023 | 0.99 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8628154 | 0.91 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7881101 | 0.91 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7880832 | 0.89 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7881109 | 0.88 | AKR1C3 (0.65) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| SCHEMBL7882011 | 0.88 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7873577 | 0.86 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7873826 | 0.86 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1DRD2DRD3 | |
| SCHEMBL8630482 | 0.85 | KDM4E (0.50) | KDM4EHSD17B10ALDH1A1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622356-B1 | Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange | SUMITOMO PHARMA (JP) | 1998-07-01 | — | — | EP | disclosed |
| EP-0622356-A1 | Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-02 | — | — | EP | disclosed |