Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.51 |
| ▸ | OXTR | P30559 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | GLP1R | P43220 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681804 | 0.88 | AVPR2 (0.48) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL4686961 | 0.88 | AVPR2 (0.54) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL7344712 | 0.88 | AVPR2 (0.65) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL7357342 | 0.86 | AVPR2 (0.61) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL7355318 | 0.82 | AVPR2 (0.71) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL7356778 | 0.82 | AVPR2 (0.65) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL4142479 | 0.81 | AVPR2 (0.76) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL7345732 | 0.81 | AVPR2 (0.70) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL7345003 | 0.81 | AVPR2 (0.60) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL7357390 | 0.80 | AVPR2 (0.62) | AVPR2AVPR1ACHRM1ABCB11HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |