Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593977 | 1.00 | FFAR1 (0.63) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL9179407 | 0.87 | FFAR1 (0.74) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL13461018 | 0.79 | FFAR1 (0.63) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL29033928 | 0.79 | FFAR1 (0.63) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL7983926 | 0.79 | FFAR1 (0.69) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL11244770 | 0.78 | FFAR1 (0.68) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL74365 | 0.78 | FFAR1 (1.00) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL10967471 | 0.78 | FFAR1 (0.67) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL2210143 | 0.78 | FFAR1 (0.61) | FFAR1ALDH1A1NPC1KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL6255246 | 0.76 | FFAR1 (0.95) | FFAR1ALDH1A1NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880504-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027181-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-07-31 | — | — | WO | disclosed |