Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627408 | 0.89 | AVPR1A (0.40) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8634013 | 0.86 | AVPR1A (0.42) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8627393 | 0.85 | AVPR1A (0.40) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8631000 | 0.83 | AVPR1A (0.39) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8628507 | 0.83 | AVPR1A (0.39) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8634475 | 0.82 | AVPR2 (0.42) | AVPR1AAVPR2KMT2ALMNATP53 | |
| Hydrochloric Acid SCHEMBL8632564 | 0.81 | AVPR2 (0.46) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8634477 | 0.80 | AVPR2 (0.38) | AVPR1AAVPR2KMT2ALMNATP53 | |
| SCHEMBL8627133 | 0.80 | AVPR2 (0.40) | AVPR1AAVPR2KMT2ALMNATP53 | |
| Hydrochloric Acid SCHEMBL8627391 | 0.79 | AVPR2 (0.42) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |