Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD1 | P49961 | 3/20 | 0.66 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.62 |
| ▸ | NADK | O95544 | 1/20 | 0.60 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082696 | 0.95 | ENTPD1 (0.73) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL374913 | 0.95 | ENTPD1 (0.73) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL374912 | 0.95 | ENTPD1 (0.73) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL30079811 | 0.95 | ENTPD1 (0.73) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL4314233 | 0.94 | ENTPD1 (0.72) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL6764984 | 0.90 | SIRT2 (0.72) | ENTPD1SIRT2SIRT1TRPM2NADK | |
| SCHEMBL4315602 | 0.90 | SIRT2 (0.72) | ENTPD1SIRT2SIRT1TRPM2NADK | |
| SCHEMBL30583439 | 0.90 | SIRT2 (0.72) | ENTPD1SIRT2SIRT1TRPM2NADK | |
| SCHEMBL8628968 | 0.89 | NADK (0.64) | ENTPD1NADK | |
| SCHEMBL28823541 | 0.89 | SIRT2 (0.71) | ENTPD1SIRT2SIRT1TRPM2NADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566140-B1 | Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof | UNITIKA LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5306629-A | Two-stage reaction using two enzymes: adenosine-5-triphosphate sulfurylase and diadenosine tetraphosphate phosphorylase as catalysts, and adenosine-5-triphosphate, polyphosphate and a sulfate as substrates | UNITIKA LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0566140-A2 | Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof | UNITIKA LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |
| EP-0247819-B1 | PROCESS FOR PRODUCING DIADENOSINE TETRAPHOSPHATE AND DERIVATIVES THEREOF | UNITIKA LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |
| US-4886749-A | Process for producing diadenosine tetraphosphate and derivatives thereof | UNITIKA LTD. (JP) | 1989-12-12 | — | — | US | disclosed |