SCHEMBL8629144

SCHEMBL8629144

CCN1CC(C)N(C(C)C)C1=O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.31
F2 P00734 1/20 0.30
ELANE P08246 1/20 0.30
CTSG P08311 1/20 0.30
CTRC Q99895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13574982 1.00 PIK3CD (0.31) PIK3CDF2ELANECTSGCTRC
SCHEMBL23607701 0.83 GAA (0.33) PIK3CD
SCHEMBL24742526 0.79
SCHEMBL23733925 0.75
SCHEMBL22872652 0.74
SCHEMBL12648596 0.74 ACE (0.35)
SCHEMBL6940554 0.74 MAPT (0.37)
SCHEMBL12594213 0.74 MAPT (0.37)
SCHEMBL14554150 0.74 ACE (0.35)
SCHEMBL12594212 0.74 MAPT (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718291-B1 Method for the preparation of triazole compounds CHUGAI PHARMACEUTICAL CO LTD (JP) 1998-07-08 EP disclosed
US-5567825-A Method for the preparation of a triazole compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1996-10-22 US disclosed
EP-0718291-A1 Method for the preparation of triazole compounds CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1996-06-26 EP disclosed