Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784535 | 0.90 | ADORA2A (0.41) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8692599 | 0.89 | ADORA2A (0.41) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8696729 | 0.89 | GRM5 (0.41) | KMT2AADORA2AADORA1ALDH1A1MAOB | |
| SCHEMBL8695612 | 0.89 | MAPT (0.41) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8693809 | 0.88 | KMT2A (0.43) | KMT2AADORA2AADORA1ALDH1A1MAOB | |
| SCHEMBL8692231 | 0.88 | ADORA2A (0.40) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8693775 | 0.88 | KMT2A (0.43) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8625972 | 0.88 | ADORA2A (0.42) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8698390 | 0.88 | MAPT (0.45) | KMT2AADORA2AADORA1ALDH1A1MAOB | |
| SCHEMBL8694286 | 0.87 | KMT2A (0.45) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| US-5807804-A | CONTROLLING WEEDS | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5710106-A | Substituted pyridine herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |