Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597805 | 0.83 | CYP3A4 (0.40) | CYP2D6HRH1CHRM1KCNH2CYP3A4 | |
| SCHEMBL10446411 | 0.74 | CFTR (0.58) | CYP3A4CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14283944 | 0.73 | CFTR (0.63) | KCNH2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17069338 | 0.73 | CFTR (0.63) | KCNH2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17071838 | 0.73 | CFTR (0.63) | KCNH2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2601115 | 0.73 | CFTR (0.63) | KCNH2CFTRSLC6A2SLC6A4SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL5999497 | 0.71 | CFTR (0.61) | KCNH2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15780702 | 0.70 | CCR4 (0.40) | CYP3A4KDM4EGAATSHR | |
| Ammonia Solution, Strong SCHEMBL354291 | 0.69 | CCR4 (0.39) | CYP3A4KDM4EGAATSHR | |
| SCHEMBL6999631 | 0.68 | TSHR (0.66) | CYP2D6HRH1CHRM1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |