SCHEMBL8629915

SCHEMBL8629915

c1ccc2c(c1)-c1c[nH]c-2n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 5/20 0.36
DCUN1D1 Q96GG9 8/20 0.34
DCUN1D2 Q6PH85 1/20 0.32
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 3/20 0.31
APOBEC3G Q9HC16 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 2/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
MPI P34949 1/20 0.31
GBA1 P04062 1/20 0.30
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28813677 0.81 DCUN1D1 (0.44) DCUN1D1DCUN1D2KDM4EALDH1A1NPC1
SCHEMBL7139471 0.81 DCUN1D1 (0.49) DCUN1D1KDM4EALDH1A1TDP1MAPT
SCHEMBL8986487 0.81 DCUN1D1 (0.49) PDGFRBDCUN1D1CASP3SENP8SENP7
SCHEMBL29785392 0.81 DCUN1D1 (0.44) DCUN1D1DCUN1D2KDM4EALDH1A1NPC1
SCHEMBL27824969 0.80 PDGFRB (0.45) PDGFRBKDM4EALDH1A1GAAHPGD
SCHEMBL17280171 0.78 DCUN1D1 (0.46) DCUN1D1DCUN1D2KDM4EALDH1A1MAPT
SCHEMBL9731133 0.77 DCUN1D1 (0.53) DCUN1D1ALDH1A1MAPTGAAHPGD
Nortopsentin D SCHEMBL29489921 0.74 PDGFRB (0.62) PDGFRBKDM4EALDH1A1TDP1MAPT
SCHEMBL27762172 0.74 PIM1 (0.41) PDGFRBDCUN1D1KDM4EMAPTMEN1
SCHEMBL27741612 0.74 PIM1 (0.38) DCUN1D1KDM4EALDH1A1NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5780820-A Film-like heater made of high crystalline graphite film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-07-14 US claimed
US-5780820-A Film-like heater made of high crystalline graphite film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-07-14 US disclosed