SCHEMBL8630149

SCHEMBL8630149

C=C(C)C(=O)OCC(CCC)(CCC)OC(=O)C(=C)C

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.42
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165954 0.96 TSHR (0.44) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL16291282 0.87 TSHR (0.42) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL16291366 0.83 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL16291137 0.83 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL3685235 0.81 TSHR (0.42) TSHRTHRBALDH1A1
SCHEMBL2017671 0.80 TSHR (0.40) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL26107150 0.80 TSHR (0.33) TSHRTHRBALDH1A1
SCHEMBL26107155 0.80 TSHR (0.40) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL8851060 0.79 TSHR (0.48) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL2245821 0.79 TSHR (0.48) TSHRTHRBALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5846640-A Polymer-fibre prepreg, a method for the preparation thereof as well as the use of said prepreg BIOXID OY (FI) 1998-12-08 US claimed