Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629645 | 1.00 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL8628061 | 1.00 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL8628056 | 1.00 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL8626976 | 0.93 | FFAR1 (0.36) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL3930745 | 0.85 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL9298296 | 0.85 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL20836039 | 0.85 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL20836041 | 0.85 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL28814697 | 0.85 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL9512070 | 0.85 | NISCH (0.37) | NISCHMAOAMAOBADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276501-B2 | Thickening compositions and thickened aqueous acid solutions | AKZO NOBEL NV (NL) | 1998-06-17 | — | — | EP | disclosed |
| US-5041239-A | Premix compositions for the preparation of thickened aqueous acid solutions | AKZO N. V. (NL) | 1991-08-20 | — | — | US | disclosed |
| US-4853146-A | Thickening compositions and thickened aqueous acid solutions | AKZO N.V. (NL) | 1989-08-01 | — | — | US | disclosed |
| EP-0276501-A2 | Thickening compositions and thickened aqueous acid solutions | Akzo Nobel N.V. (NL) | 1988-08-03 | — | — | EP | disclosed |