Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528445 | 1.00 | SLC2A1 (0.57) | SLC2A1CA2OPRM1CSNK1ESPHK1 | |
| SCHEMBL28741672 | 1.00 | SLC2A1 (0.57) | SLC2A1CA2OPRM1CSNK1ESPHK1 | |
| SCHEMBL15709694 | 0.92 | SLC2A1 (0.47) | SLC2A1CA2OPRM1CSNK1E | |
| SCHEMBL27511254 | 0.84 | SLC2A1 (0.39) | SLC2A1CA2 | |
| SCHEMBL28381908 | 0.83 | SLC2A1 (0.39) | SLC2A1CA2LMNABLMHTR2A | |
| Water SCHEMBL9062617 | 0.83 | SLC2A1 (0.58) | SLC2A1CA2OPRM1CSNK1EHTR2A | |
| Water SCHEMBL28159332 | 0.83 | SLC2A1 (0.58) | SLC2A1CA2OPRM1CSNK1EHTR2A | |
| SCHEMBL21753852 | 0.81 | SLC2A1 (0.38) | SLC2A1SPHK1 | |
| SCHEMBL10357844 | 0.81 | NR1I2 (0.46) | SLC2A1OPRM1CSNK1ELMNANR1I2 | |
| SCHEMBL982650 | 0.81 | NR1I2 (0.46) | SLC2A1OPRM1CSNK1ELMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929557-A2 | (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014454-A2 | (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1998-04-09 | — | — | WO | disclosed |