Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144072 | 0.76 | HSD17B10 (0.67) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL7364591 | 0.76 | HSD17B10 (0.71) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL9661198 | 0.75 | HSD17B10 (0.74) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL15143214 | 0.73 | HSD17B10 (0.67) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL9661237 | 0.73 | HSD17B10 (1.00) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL9660330 | 0.73 | HSD17B10 (0.77) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL2797516 | 0.72 | HSD17B10 (0.65) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL21505100 | 0.72 | HSD17B10 (0.65) | HSD17B10POLBCRBNKMT2AALDH1A1 | |
| SCHEMBL30149651 | 0.72 | HSD17B10 (0.65) | HSD17B10POLBKMT2AALDH1A1HPGD | |
| SCHEMBL8628655 | 0.72 | POLB (0.65) | HSD17B10POLBCRBNKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668855-B1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS FOR USE AS CHELATING AGENTS | AMERSHAM INT PLC (GB) | 1998-06-24 | — | — | EP | disclosed |