Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MECP2 | P51608 | 1/20 | 0.46 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.46 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.46 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.46 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625316 | 0.74 | HSD17B10 (0.42) | KDRMEN1KMT2AGFERNPC1 | |
| SCHEMBL221242 | 0.72 | KMT2A (0.76) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL29391624 | 0.72 | KMT2A (0.76) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL3951276 | 0.71 | MEN1 (0.67) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL29544002 | 0.71 | MEN1 (0.67) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL15688032 | 0.70 | MECP2 (0.51) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL6121259 | 0.70 | KDR (0.54) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL11133606 | 0.70 | KMT2A (0.73) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL4243882 | 0.70 | KMT2A (0.73) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL6175584 | 0.70 | KMT2A (0.73) | KDRMEN1KMT2AMAPK10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |