Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630900 | 0.95 | TDP1 (0.52) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8630065 | 0.93 | TDP1 (0.51) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8631782 | 0.92 | MEN1 (0.44) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8632459 | 0.87 | TDP1 (0.56) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8633719 | 0.87 | MEN1 (0.53) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8634208 | 0.87 | MEN1 (0.58) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8633773 | 0.85 | MEN1 (0.57) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8634602 | 0.82 | TDP1 (0.56) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8630069 | 0.82 | MEN1 (0.48) | MEN1KMT2AGAATDP1CA12 | |
| SCHEMBL8633552 | 0.81 | TDP1 (0.63) | MEN1KMT2AGAATDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |