Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 8/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630072 | 0.92 | FGFR1 (0.46) | EP300FGFR1SLC22A6ENPEPMAPT | |
| SCHEMBL5296992 | 0.77 | FGFR1 (0.50) | FGFR1SLC22A6CYP2D6 | |
| SCHEMBL7270586 | 0.77 | FGFR1 (0.50) | FGFR1SLC22A6CYP2D6 | |
| SCHEMBL30468121 | 0.77 | FGFR1 (0.47) | EP300FGFR1SLC22A6MAPTCYP2D6 | |
| SCHEMBL1672081 | 0.74 | KMT2A (0.46) | EP300FGFR1SLC22A6MAPT | |
| SCHEMBL13596 | 0.73 | FGFR1 (0.43) | EP300FGFR1SLC22A6MAPTCYP2D6 | |
| SCHEMBL14478248 | 0.72 | FGFR1 (0.50) | FGFR1SLC22A6 | |
| SCHEMBL7269776 | 0.71 | FGFR1 (0.52) | EP300FGFR1SLC22A6MAPT | |
| SCHEMBL12652844 | 0.70 | FGFR1 (0.51) | EP300FGFR1SLC22A6MAPT | |
| SCHEMBL14082 | 0.70 | FGFR1 (0.38) | EP300FGFR1SLC22A6CYP2D6DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705333-A | Peptide-based nucleic acid mimics(PENAMS) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-01-06 | — | — | US | disclosed |