Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973808 | 1.00 | PPARG (0.36) | PPARGPPARDPPARAALDH1A1MAPT | |
| SCHEMBL1973807 | 1.00 | PPARG (0.36) | PPARGPPARDPPARAALDH1A1MAPT | |
| SCHEMBL18877268 | 1.00 | PPARG (0.36) | PPARGPPARDPPARAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL29046719 | 0.98 | PPARG (0.35) | PPARGPPARDPPARAALDH1A1MAPT | |
| SCHEMBL29277561 | 0.88 | CNR1 (0.39) | PPARGPPARDPPARAALDH1A1MAPT | |
| SCHEMBL4161786 | 0.82 | — | — | |
| SCHEMBL13384365 | 0.80 | CYP1A2 (0.54) | PPARGPPARDPPARAGRIK1GRIK2 | |
| SCHEMBL2160963 | 0.80 | CYP1A2 (0.54) | PPARGPPARDPPARAGRIK1GRIK2 | |
| SCHEMBL2160966 | 0.80 | CYP1A2 (0.54) | PPARGPPARDPPARAGRIK1GRIK2 | |
| SCHEMBL8632405 | 0.80 | CYP1A2 (0.54) | PPARGPPARDPPARAGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811462-A | (BICYCLO(2.2.1)HEPT-5'-EN-2'-YL-CARBONYL)AMINO-3-HYDROXY DERIVATIVES | MERCK & CO., INC. (US) | 1998-09-22 | — | — | US | disclosed |