⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957860 | 1.00 | — | — | |
| SCHEMBL11229 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28934945 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL5755909 | 0.96 | — | — | |
| Benzene SCHEMBL27964485 | 0.89 | TSHR (0.80) | — | |
| SCHEMBL24269491 | 0.82 | — | — | |
| SCHEMBL16556492 | 0.82 | — | — | |
| SCHEMBL635314 | 0.82 | — | — | |
| SCHEMBL8181574 | 0.82 | — | — | |
| SCHEMBL12603758 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112280761-B | Recombinant transaminase, mutant of recombinant transaminase and application of mutant | 清华大学 | 2022-04-12 | — | — | CN | claimed |
| CN-112280761-A | Recombinant transaminase, mutant of recombinant transaminase and application of mutant | 清华大学 | 2021-01-29 | — | — | CN | claimed |
| US-20250236851-A1 | Pseudomonas Putida omega-Transaminase Gene with Broad Substrate Spectrum and Application Thereof | SHANXI UNIVERSITY (CN) | 2025-07-24 | — | — | US | disclosed |
| CN-118291419-A | Mutant of thermostable aminotransferase and application thereof | 清华大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-117925654-A | Pseudomonas putida omega-aminotransferase gene with wide substrate spectrum and application thereof | 山西大学 | 2024-04-26 | — | — | CN | disclosed |
| US-20230174567-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | MERCK SHARP & DOHME LLC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230135560-A1 | GEM-DISUBSTITUTED PIPERIDINE MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230126662-A1 | SPIROCYCLIC PIPERIDINE MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-04-27 | — | — | US | disclosed |
| WO-2023018473-A1 | COMBINED DETERMINATION OF THE CONCENTRATION AND ENANTIOMERIC COMPOSITION OF CHIRAL COMPOUNDS USING SINGLE CHIROPTICAL ASSAY | GEORGETOWN UNIVERSITY (US) | 2023-02-16 | — | — | WO | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-112280761-B | Recombinant transaminase, mutant of recombinant transaminase and application of mutant | 清华大学 | 2022-04-12 | — | — | CN | disclosed |
| US-7491741-B2 | Diaminopropionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7456194-B2 | Imidazo-fused oxazolo [4,5-b]pyridine and imidazo-fused thiazolo[4,5-b]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-07-12 | — | — | US | disclosed |
| US-20070155671-A1 | Diaminopropionic acid derivatives | FOTOUHI NADER | 2007-07-05 | — | — | US | disclosed |
| US-20070155671-A1 | Diaminopropionic acid derivatives | FOTOUHI NADER | 2007-07-05 | — | — | US | disclosed |
| US-7217728-B2 | Diaminopropionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217728-B2 | Diaminopropionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-05-15 | — | — | US | disclosed |
| EP-1089980-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067221-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | disclosed |