Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632538 | 1.00 | ATM (0.43) | ATMPDE8BMEN1KMT2AFKBP1A | |
| SCHEMBL9210070 | 0.95 | ATM (0.44) | ATMPDE8BMEN1KMT2AFKBP1A | |
| SCHEMBL5940127 | 0.88 | ATM (0.43) | ATMPDE8BMEN1KMT2AFKBP1A | |
| SCHEMBL8630832 | 0.86 | SMN1; SMN2 (0.42) | ATMMEN1KMT2AHSD17B10KDM1A | |
| SCHEMBL8634312 | 0.86 | SMN1; SMN2 (0.42) | ATMMEN1KMT2AHSD17B10KDM1A | |
| SCHEMBL8630831 | 0.86 | SMN1; SMN2 (0.42) | ATMMEN1KMT2AHSD17B10KDM1A | |
| SCHEMBL8634310 | 0.86 | SMN1; SMN2 (0.42) | ATMMEN1KMT2AHSD17B10KDM1A | |
| SCHEMBL5940343 | 0.83 | ATM (0.43) | ATMPDE8BMEN1KMT2AHSD17B10 | |
| SCHEMBL13996061 | 0.81 | ATM (0.46) | ATMPDE8BKMT2AHSD17B10KDM1A | |
| SCHEMBL24739379 | 0.81 | ATM (0.48) | ATMPDE8BMEN1KMT2AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |