SCHEMBL8632662

SCHEMBL8632662

C1=CC2CCC1C2.C=CCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
ALDH1A1 P00352 1/20 0.46
FAAH O00519 2/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22203987 1.00 TSHR (0.59) TSHRALDH1A1FAAHTRPV1
SCHEMBL8088836 0.92 TSHR (0.56) TSHRALDH1A1
SCHEMBL8415839 0.92 TSHR (0.56) TSHRALDH1A1
Ethylene SCHEMBL27411688 0.91 TSHR (0.54) TSHRALDH1A1
Adamantane SCHEMBL28142202 0.78 TSHR (0.73) TSHRALDH1A1FAAHTRPV1
SCHEMBL23539923 0.77 TSHR (1.00) TSHRALDH1A1FAAHTRPV1
SCHEMBL11900218 0.77 TSHR (1.00) TSHRALDH1A1FAAHTRPV1
SCHEMBL7153127 0.77 TSHR (1.00) TSHRALDH1A1FAAHTRPV1
SCHEMBL22164116 0.77 TSHR (1.00) TSHRALDH1A1FAAHTRPV1
SCHEMBL2848855 0.77 TSHR (1.00) TSHRALDH1A1FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5741869-A REACTION MIXTURE FOR FORMING ADDITION POLYMER COMPRISING NORBORNENE-FUNCTIONAL MONOMER, SOLVENT, GROUP 8 METAL-CONTAINING CATALYST SYSTEM, CHAIN TRANSFER AGENT THE B.F. GOODRICH COMPANY (US) 1998-04-21 US disclosed
US-5571881-A Addition polymers derived from norbornene-functional monomers and process therefor THE B. F. GOODRICH COMPANY (US) 1996-11-05 US disclosed
US-5569730-A HAVING TERMINAL END GROUP DERIVED FROM CHAIN TRANSFER AGENT CONTAINING TERMINAL OLEFINIC DOUBLE BOND THE B. F. GOODRICH COMPANY (US) 1996-10-29 US disclosed
EP-0729480-A1 ADDITION POLYMERS DERIVED FROM NORBORNENE-FUNCTIONAL MONOMERS AND PROCESS THEREFOR The B.F. Goodrich Company (US) 1996-09-04 EP disclosed
US-5468819-A Process for making polymers containing a norbornene repeating unit by addition polymerization using an organo (nickel or palladium) complex THE B.F. GOODRICH COMPANY (US) 1995-11-21 US disclosed
WO-1995014048-A9 ADDITION POLYMERS DERIVED FROM NORBORNENE-FUNCTIONAL MONOMERS AND PROCESS THEREFOR 1995-07-27 WO disclosed
WO-1995014048-A1 ADDITION POLYMERS DERIVED FROM NORBORNENE-FUNCTIONAL MONOMERS AND PROCESS THEREFOR THE B.F. GOODRICH COMPANY (US) 1995-05-26 WO disclosed