Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631222 | 0.80 | CYP3A4 (0.40) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7790883 | 0.72 | CYP3A4 (0.50) | ALDH1A1SMN1; SMN2MAPTCYP3A4TSHR | |
| SCHEMBL8631993 | 0.71 | MAPT (0.34) | LMNAMAPTATML3MBTL1CYP1A2 | |
| SCHEMBL7794842 | 0.68 | KMT2A (0.43) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7785295 | 0.67 | CYP3A4 (0.44) | ALDH1A1LMNASMN1; SMN2MAPK1CYP3A4 | |
| Vinyl Chloride SCHEMBL8855429 | 0.67 | CYP3A4 (0.89) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| Bicarbonate SCHEMBL20838538 | 0.66 | CYP3A4 (0.92) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL16371573 | 0.66 | CYP3A4 (1.00) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL29362146 | 0.66 | CYP3A4 (1.00) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL27474785 | 0.66 | CYP3A4 (1.00) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723610-A | Alcohol reactants for forming phenylpyrimidine derivatives and process for preparing said alcohols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |