Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.42 |
| ▸ | HMGCR | P04035 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800093 | 0.82 | ABCG2 (0.42) | PTPN7HMGCRMEN1ALDH1A1KMT2A | |
| SCHEMBL11800091 | 0.82 | ABCG2 (0.42) | PTPN7HMGCRMEN1ALDH1A1KMT2A | |
| SCHEMBL9715105 | 0.79 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL8463186 | 0.79 | HMGCR (0.47) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL8463179 | 0.79 | HMGCR (0.47) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL31509137 | 0.79 | ABCG2 (0.49) | PTPN7HMGCRRECQLMEN1USP2 | |
| SCHEMBL11178921 | 0.79 | ABCG2 (0.49) | PTPN7HMGCRRECQLMEN1USP2 | |
| SCHEMBL9715107 | 0.79 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL14691063 | 0.78 | HMGCR (0.45) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL14691061 | 0.78 | HMGCR (0.45) | PTPN7HMGCRRECQLTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691963-B1 | HEPOXILIN ANALOGS USEFUL AS ANTI-INFLAMMATORY AGENTS | HSC RES DEV LP (CA) | 1998-07-15 | — | — | EP | disclosed |
| US-5616607-A | TREATS INFLAMMATION, ASTHMA, HYPERTENSION, MIGRAINE AND SEPTIC SHOCK | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 1997-04-01 | — | — | US | disclosed |
| EP-0691963-A1 | HEPOXILIN ANALOGS USEFUL AS ANTI-INFLAMMATORY AGENTS | HSC Research and Development Limited Partnership (CA) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022848-A1 | HEPOXILIN ANALOGS USEFUL AS ANTI-INFLAMMATORY AGENTS | PACE ASCIAK CECIL R (CA) | 1994-10-13 | — | — | WO | disclosed |