Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23866601 | 1.00 | CYP2D6 (0.56) | CYP2D6CYP2C19KMT2AMEN1MMP1 | |
| SCHEMBL2315958 | 1.00 | CYP2D6 (0.56) | CYP2D6CYP2C19KMT2AMEN1MMP1 | |
| SCHEMBL8195763 | 0.84 | MEN1 (0.50) | CYP2D6CYP2C19KMT2AMEN1MMP1 | |
| SCHEMBL1582718 | 0.84 | MEN1 (0.50) | CYP2D6CYP2C19KMT2AMEN1MMP1 | |
| SCHEMBL3354440 | 0.81 | CYP2D6 (0.59) | CYP2D6CYP2C19KMT2AMEN1MMP1 | |
| SCHEMBL1583004 | 0.80 | MEN1 (0.47) | CYP2D6CYP2C19KMT2AMEN1MMP1 | |
| SCHEMBL15374903 | 0.78 | MEN1 (0.45) | CYP2D6CYP2C19KMT2AMEN1HPGD | |
| SCHEMBL18212154 | 0.78 | MEN1 (0.45) | CYP2D6CYP2C19KMT2AMEN1GAA | |
| SCHEMBL15374899 | 0.78 | MEN1 (0.45) | CYP2D6CYP2C19KMT2AMEN1HPGD | |
| SCHEMBL18212166 | 0.78 | MEN1 (0.45) | CYP2D6CYP2C19KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821675-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033176-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |