Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 9/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.41 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559593 | 0.81 | CDK5 (0.42) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL1596530 | 0.81 | CDK5 (0.42) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL4298369 | 0.73 | CDK5 (0.50) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL4298365 | 0.73 | CDK5 (0.50) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL426656 | 0.69 | GRM5 (0.51) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL9954250 | 0.69 | CDK5 (0.46) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL29564444 | 0.69 | CDK5 (0.46) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL13865788 | 0.69 | CDK5 (0.51) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL6234455 | 0.69 | CDK5 (0.46) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL30676854 | 0.69 | GRM5 (0.51) | CDK5CDK5R1CCNA2CDK2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |