Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.69 |
| ▸ | ACE | P12821 | 6/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579605 | 1.00 | MME (0.69) | MMEACEFCER2KDM4EALDH1A1 | |
| SCHEMBL7417946 | 0.89 | MME (0.53) | MMEACEFCER2 | |
| SCHEMBL7417942 | 0.89 | MME (0.53) | MMEACEFCER2 | |
| SCHEMBL7416489 | 0.88 | MME (0.67) | MMEACEFCER2 | |
| SCHEMBL7416486 | 0.88 | MME (0.67) | MMEACEFCER2 | |
| SCHEMBL7415400 | 0.85 | MME (0.50) | MMEACEKDM4EALDH1A1 | |
| SCHEMBL8578183 | 0.84 | MME (0.49) | MMEACEFCER2KDM4EALDH1A1 | |
| SCHEMBL8653461 | 0.84 | MME (0.49) | MMEACEFCER2KDM4EALDH1A1 | |
| SCHEMBL6442555 | 0.76 | MME (0.64) | MMEACE | |
| SCHEMBL6442561 | 0.76 | MME (0.64) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609310-B1 | N-(MERCAPTOACYL)AMINO ACIDS, METHODS OF THEIR PREPARATION AND THERAPEUTIC USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INST NAT SANTE RECH MED (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5591891-A | PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-01-07 | — | — | US | disclosed |
| WO-1994017036-A1 | S-LIPOPHILIC ALIPHATIC CARBONYL [N-MERCAPTOACYL-(AMINO ACID OR PEPTIDE)] COMPOUNDS AS ANTIHYPERTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-08-04 | — | — | WO | disclosed |
| EP-0539848-A1 | N-(mercaptoacyl)amino acids, methods of their preparation and therapeutic use, and pharmaceutical compositions containing them | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-05-05 | — | — | EP | disclosed |