Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385084 | 1.00 | KDM4E (0.46) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL7384022 | 0.95 | NR1H2 (0.46) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL5080006 | 0.89 | KDM4E (0.51) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL6059034 | 0.86 | NR1H2 (0.43) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL6749438 | 0.86 | NR1H2 (0.45) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL7350839 | 0.85 | HPGD (0.46) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL23849943 | 0.85 | DPP4 (0.46) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL9891005 | 0.85 | NR1H2 (0.44) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL28646412 | 0.85 | DPP4 (0.46) | KDM4EPKMNR1H2HPGDGPR119 | |
| SCHEMBL18497663 | 0.84 | NR1H2 (0.51) | KDM4EPKMNR1H2HPGDGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |