Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18301471 | 0.95 | CYP1A2 (0.59) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL31106560 | 0.94 | CYP1A2 (0.67) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL1822554 | 0.94 | CYP1A2 (0.67) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL29992091 | 0.94 | CYP1A2 (0.71) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL30141847 | 0.94 | CYP1A2 (0.71) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL20804356 | 0.94 | CYP1A2 (0.71) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL1331974 | 0.94 | CYP1A2 (0.71) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL1333260 | 0.94 | CYP1A2 (0.71) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL3161186 | 0.92 | CYP2C19 (0.65) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28330520 | 0.92 | CYP1A2 (0.65) | CYP1A2CYP2C19KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708022-A | RUTHENIUM COMPLEXES | PROCEPT, INC. (US) | 1998-01-13 | — | — | US | claimed |
| US-5708022-A | RUTHENIUM COMPLEXES | PROCEPT, INC. (US) | 1998-01-13 | — | — | US | disclosed |
| WO-1996013510-A1 | RUTHENIUM COMPLEXES AND THEIR USE AS IMMUNOSUPPRESSIVE AGENTS | PROCEPT, INC. (US) | 1996-05-09 | — | — | WO | disclosed |