Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630676 | 0.92 | TDP1 (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8633719 | 0.91 | MEN1 (0.53) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8633229 | 0.90 | MEN1 (0.53) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8634602 | 0.88 | TDP1 (0.56) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8631782 | 0.86 | MEN1 (0.44) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8630770 | 0.82 | TDP1 (0.56) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8634208 | 0.80 | MEN1 (0.58) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL21724670 | 0.80 | TDP1 (0.51) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8630894 | 0.79 | TDP1 (0.61) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8633773 | 0.79 | MEN1 (0.57) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |