Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634496 | 0.79 | TSHR (0.61) | TSHR | |
| SCHEMBL8529289 | 0.72 | TSHR (0.52) | TSHR | |
| SCHEMBL28099720 | 0.70 | TSHR (0.50) | TSHR | |
| SCHEMBL19518806 | 0.68 | — | — | |
| SCHEMBL15906597 | 0.68 | TSHR (0.48) | TSHR | |
| SCHEMBL20379124 | 0.68 | TSHR (0.48) | TSHR | |
| SCHEMBL18721104 | 0.68 | TSHR (0.42) | TSHR | |
| SCHEMBL6543364 | 0.68 | — | — | |
| SCHEMBL16621830 | 0.68 | — | — | |
| SCHEMBL2669556 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053911-C | Closed-large ring lactone and closed-azalactone group new compounds and preparation process thereof | PLIVA PHARM & CHEM WORKS (HR) | 2000-06-28 | — | — | CN | disclosed |
| US-5721346-A | Compounds of the secomacrolide and secoazalide class and a process for the preparation thereof | PLIVA, FARMACEUTSKA, KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1998-02-24 | — | — | US | disclosed |
| CN-1133294-A | Closed-large ring lactone and closed-azalactone group new compounds and preparation process thereof | PLIVA PHARM & CHEM WORKS (HR) | 1996-10-16 | — | — | CN | disclosed |
| EP-0735041-A1 | New compounds of the secomacrolide and secoazalide class and a process for the preparation thereof | PLIVA farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvo (HR) | 1996-10-02 | — | — | EP | disclosed |