SCHEMBL8634500

SCHEMBL8634500

C/C(=C\CC(O)C(O)CO)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.34
CD81 P60033 1/20 0.33
LMNA P02545 1/20 0.32
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
OR51E2 Q9H255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3273630 1.00 PDE4A (0.34) PDE4ACD81LMNAUSP2SLCO1B1
SCHEMBL1513883 0.88 PDE4A (0.45) PDE4ACD81LMNAUSP2SLCO1B1
SCHEMBL622513 0.88 PDE4A (0.41) PDE4ACD81LMNAUSP2SLCO1B1
SCHEMBL9056020 0.88 PDE4A (0.41) PDE4ACD81LMNAUSP2SLCO1B1
SCHEMBL288639 0.81 CD81 (0.33) CD81LMNAOR51E2
SCHEMBL2594210 0.81 CD81 (0.33) CD81
SCHEMBL8624309 0.81 CD81 (0.33) CD81LMNAOR51E2
SCHEMBL243508 0.81 CD81 (0.33) CD81LMNAOR51E2
SCHEMBL2594207 0.81 CD81 (0.33) CD81
Water SCHEMBL10629819 0.79 OR51E2 (0.36) CD81LMNAOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0448780-B1 Electrophotographic imaging member XEROX CORP (US) 1998-04-08 EP disclosed
US-5660961-A HAVING BLOCKING LAYER COMPRISING SOLID FINELY DIVIDED LIGHT SCATTERING INORGANIC PARTICLES OF AMORPHOUS SILICA AND/OR MINERALS DISPERSED IN MATRIX COMPRISING REACTION PRODUCT OF FILM FORMING POLYMER AND ORGANOSILANE XEROX CORPORATION 1997-08-26 US disclosed
EP-0435635-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-18 EP disclosed
EP-0435633-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-11 EP disclosed
EP-0435634-B1 Conductive and blocking layers for electrophotographic imaging members XEROX CORP (US) 1995-11-02 EP disclosed
US-5460911-A Electrophotographic imaging member free of reflection interference XEROX CORPORATION (US) 1995-10-24 US disclosed
US-5385796-A Durable, dark stable, waterproof xerographic materials which charge to high voltage XEROX CORPORATION (US) 1995-01-31 US disclosed
US-5244762-A Polymers of hydroxyacrylic amides and hydroxyacrylic esters, hydroxy group modified to become ether, ester, sulfonate, carbamate XEROX CORPORATION (US) 1993-09-14 US disclosed
US-5063128-A Forming a semitransparent conductive layer of particles having acidic surfaces and a polymer; xerography; humidity resistance; durability XEROX CORPORATION (US) 1991-11-05 US disclosed
US-5063125-A For electrographic imaging XEROX CORPORATION (US) 1991-11-05 US disclosed
EP-0448780-A1 Electrophotographic imaging member XEROX CORPORATION (US) 1991-10-02 EP disclosed
EP-0435633-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP disclosed
EP-0435635-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP disclosed
EP-0435634-A2 Conductive and blocking layers for electrophotographic imaging members XEROX CORPORATION (US) 1991-07-03 EP disclosed
US-4988597-A MULTILAYER ELECTROGRAPHY IMAGING PROCESS AND ELEMENT, A PHOTOCONDUCTIVE LAYER, AN ELECTROCONDUCTIVE LAYER OF A PARTIALLY CRO SSLINKED POLYMER OF ACRYLAMIDOGLYCOLATE ALKYL ETHER XEROX CORPORATION (US) 1991-01-29 US disclosed