SCHEMBL863465

SCHEMBL863465

C=C(c1ccccc1CO[Si](C)(C)C(C)(C)C)c1ccccc1CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.45
PREP P48147 1/20 0.33
HPGD P15428 2/20 0.33
IDO1 P14902 4/20 0.33
KMT2A Q03164 1/20 0.32
TACR1 P25103 1/20 0.32
ALDH1A1 P00352 3/20 0.31
LMNA P02545 1/20 0.31
HIF1A Q16665 1/20 0.31
NPC1 O15118 1/20 0.31
HCRTR2 O43614 1/20 0.31
KDM4E B2RXH2 1/20 0.30
RCE1 Q9Y256 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673753 0.84 BACE1 (0.49) BACE1KMT2AALDH1A1LMNAHIF1A
SCHEMBL31094071 0.84 BACE1 (0.49) BACE1KMT2AALDH1A1LMNAHIF1A
SCHEMBL29703037 0.83 BACE1 (0.49) BACE1HPGDKMT2ATACR1ALDH1A1
SCHEMBL22343654 0.83 BACE1 (0.49) BACE1HPGDKMT2ATACR1ALDH1A1
SCHEMBL7171858 0.82 BACE1 (0.38) BACE1HPGDALDH1A1HCRTR2KDM4E
SCHEMBL4609411 0.80 BACE1 (0.49) BACE1HPGDKMT2ATACR1ALDH1A1
SCHEMBL31371104 0.79 IDO1 (0.53) BACE1IDO1ALDH1A1HIF1A
SCHEMBL2750402 0.79 BACE1 (0.47) BACE1HPGDIDO1KMT2ATACR1
SCHEMBL2769611 0.79 IDO1 (0.53) BACE1IDO1ALDH1A1HIF1A
SCHEMBL4609055 0.78 BACE1 (0.45) BACE1HPGDALDH1A1LMNAHCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077085-A1 POSITIVE ELECTRODE FOR NON-AQUEOUS ELECTROLYTE BATTERYAND NON-AQUEOUS ELECTROLYTE BATTERY SAKITANI NOBUHIRO (JP) 2012-03-29 US disclosed
US-7968229-B2 Positive electrode for non-aqueous electrolyte battery and non-aqueous electrolyte battery SANYO ELECTRIC CO., LTD. (JP) 2011-06-28 US disclosed
US-20090246630-A1 Positive electrode for non-aqueous electrolyte battery and non-aqueous electrolyte battery NIPPON SODA CO., LTD. (JP) 2009-10-01 US disclosed