Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818438 | 0.86 | HPGD (0.37) | HPGDKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL7413304 | 0.83 | KDM4E (0.42) | HPGDKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL4572613 | 0.75 | HPGD (0.35) | HPGDKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL11825483 | 0.73 | HPGD (0.36) | HPGDKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL9276486 | 0.71 | DDB1 (0.34) | HPGDKDM4ELMNADDB1CRBN | |
| SCHEMBL10888602 | 0.70 | TP53 (0.42) | HPGDKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL8636494 | 0.70 | HTT (0.34) | ALDH1A1ALOX5POLBKMT2A | |
| SCHEMBL3506615 | 0.69 | HPGD (0.35) | HPGDKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL5496057 | 0.67 | KDM4E (0.41) | HPGDKDM4ELMNAALDH1A1TP53 | |
| SCHEMBL28886962 | 0.67 | TSHR (0.41) | HPGDKDM4ELMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591763-B1 | Use of thioalkanediones as flavouring agents | HAARMANN & REIMER GMBH (DE) | 1998-07-29 | — | — | EP | disclosed |
| US-5466827-A | IMPARTING A MEATY AROMA TO A FOOD | HAARMANN & REIMER GMBH (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0591763-A1 | Use of thioalkanediones as flavouring agents | HAARMANN & REIMER GMBH (DE) | 1994-04-13 | — | — | EP | disclosed |