Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 11/20 | 0.57 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637496 | 0.88 | SRD5A2 (0.74) | SRD5A2SRD5A1 | |
| SCHEMBL8634066 | 0.86 | SRD5A2 (0.62) | SRD5A2SRD5A1 | |
| SCHEMBL9009529 | 0.86 | SRD5A2 (0.62) | SRD5A2SRD5A1 | |
| SCHEMBL8630741 | 0.83 | SRD5A2 (0.58) | SRD5A2SRD5A1 | |
| SCHEMBL8630271 | 0.81 | SRD5A2 (0.71) | SRD5A2SRD5A1 | |
| SCHEMBL8634553 | 0.81 | SRD5A2 (0.71) | SRD5A2SRD5A1 | |
| SCHEMBL8634952 | 0.81 | SRD5A2 (0.75) | SRD5A2SRD5A1 | |
| SCHEMBL8633739 | 0.81 | SRD5A2 (0.75) | SRD5A2SRD5A1 | |
| SCHEMBL8631020 | 0.80 | SRD5A2 (0.72) | SRD5A2SRD5A1 | |
| SCHEMBL8630590 | 0.80 | SRD5A2 (0.72) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760025-A | ADMINISTERING TESTOSTERONE 5A-REDUCTASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5717088-A | REACTING WITH A CYANOPHOSPHATE IN THE PRESENCE OF AN ALKALI METAL CYANIDE | SANKYO COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5698720-A | INTERMEDIATES FOR TESTOSTERONE 5-ALPHA-REDUCTASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0567271-B1 | Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses | SANKYO CO (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0725074-A2 | Compounds suitable for use as intermediates in the preparation of Androst-3,5-dien-3-carboxy derivatives | SANKYO COMPANY LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |
| US-5536714-A | Steroid derivatives for the treatment of prostatic hypertrophy their preparation and uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-16 | — | — | US | disclosed |