SCHEMBL8635555

SCHEMBL8635555

CCN(c1ccncc1)n1ccc2cc([N+](=O)[O-])ccc21

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 12/20 0.60
CYP1A2 P05177 1/20 0.39
GLS O94925 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7611251 0.84 SLC6A2 (0.62) SLC6A2
Fumaric Acid SCHEMBL7610905 0.77 SLC6A2 (0.53) SLC6A2
Fumaric Acid SCHEMBL7610902 0.77 SLC6A2 (0.53) SLC6A2
Maleic Acid SCHEMBL7610897 0.77 SLC6A2 (0.53) SLC6A2
SCHEMBL7613957 0.75 SLC6A2 (1.00) SLC6A2
SCHEMBL716278 0.71 SLC6A2 (0.61) SLC6A2GLS
SCHEMBL7079675 0.71 SLC6A2 (0.57) SLC6A2
SCHEMBL2420811 0.69 CYP1A2 (0.53) SLC6A2CYP1A2GLS
SCHEMBL8441967 0.69 SLC6A2 (0.73) SLC6A2
SCHEMBL7612021 0.69 SLC6A2 (1.00) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776955-A Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents HOECHST MARION ROUSSEL, INC. 1998-07-07 US claimed