SCHEMBL8635652

SCHEMBL8635652

[C]1CC(c2ccccc2)C1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
SLC18A3 Q16572 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
TSHR P16473 1/20 0.40
AKR1C3 P42330 1/20 0.39
AKR1C1 Q04828 1/20 0.39
MAOA P21397 6/20 0.39
MAOB P27338 6/20 0.39
KDM1A O60341 4/20 0.39
CYP2C19 P33261 4/20 0.39
CYP2B6 P20813 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9390223 0.76 TAAR1 (0.47) GAAMAPTTSHRAKR1C3MAOB
SCHEMBL9541250 0.74 SLC18A3 (0.54) GAAMAPTSLC18A3SIGMAR1TSHR
SCHEMBL2766491 0.73 SLC18A3 (0.52) GAAMAPTSLC18A3SIGMAR1TSHR
SCHEMBL41763 0.73
SCHEMBL190417 0.73 SLC18A3 (0.67) GAAMAPTSLC18A3SIGMAR1AKR1C3
SCHEMBL11661537 0.73 SLC18A3 (0.52) GAAMAPTSLC18A3SIGMAR1TSHR
Benzene SCHEMBL23070411 0.71 SLC18A3 (0.64) GAAMAPTSLC18A3SIGMAR1AKR1C3
Hydrogen Peroxide SCHEMBL2353767 0.71 SLC18A3 (0.64) SLC18A3SIGMAR1TSHRAKR1C3AKR1C1
Ammonia Solution, Strong SCHEMBL3932661 0.71 SLC18A3 (0.64) GAAMAPTSLC18A3SIGMAR1AKR1C3
Hydrochloric Acid SCHEMBL29241797 0.71 SLC18A3 (0.64) GAAMAPTSLC18A3SIGMAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726344-A Enantiomeric enrichment of bicyclic alcohols BEND RESEARCH, INC. (US) 1998-03-10 US disclosed