SCHEMBL8635934

SCHEMBL8635934

CC1COC1.CCCCCC1CCOC1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.46
EPHX1 P07099 1/20 0.41
ALDH1A1 P00352 1/20 0.39
PKM P14618 1/20 0.39
HTT P42858 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TLR7 Q9NYK1 4/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
DRD4 P21917 1/20 0.33
SPHK2 Q9NRA0 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7908823 0.92 CYP1A2 (0.52) CYP1A2EPHX1ALDH1A1PKMHTT
SCHEMBL14040310 0.90 CYP1A2 (0.50) CYP1A2EPHX1ALDH1A1PKMHTT
SCHEMBL3987478 0.90 CYP1A2 (0.50) CYP1A2EPHX1ALDH1A1PKMHTT
SCHEMBL6130811 0.86
SCHEMBL12289432 0.86
SCHEMBL4910497 0.81 CYP1A2 (0.48) CYP1A2EPHX1ALDH1A1PKMHTT
SCHEMBL1603327 0.80 CYP1A2 (0.55) CYP1A2EPHX1ALDH1A1PKMHTT
SCHEMBL10697801 0.80
SCHEMBL4906247 0.79 EPHX1 (0.47) CYP1A2EPHX1ALDH1A1PKMHTT
SCHEMBL4906446 0.79 EPHX1 (0.47) CYP1A2EPHX1ALDH1A1PKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0335499-B1 Method of producing thermoplastic elastomers having alternate crystalline structure for use as binders in high-energy compositions THIOKOL CORP (US) 1998-07-15 EP claimed