Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369920 | 1.00 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TAOK1LTA4H | |
| SCHEMBL7371529 | 1.00 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TAOK1LTA4H | |
| SCHEMBL8635445 | 0.90 | KMT2A (0.43) | LTA4HKMT2AEPHX2KDM1AMAOB | |
| SCHEMBL8635440 | 0.90 | KMT2A (0.43) | LTA4HKMT2AEPHX2KDM1AMAOB | |
| SCHEMBL8635442 | 0.90 | KMT2A (0.43) | LTA4HKMT2AEPHX2KDM1AMAOB | |
| SCHEMBL7375058 | 0.88 | KDM1A (0.46) | KMT2AEPHX2KDM1AMAOBMAOA | |
| SCHEMBL8635984 | 0.88 | KDM1A (0.46) | KMT2AEPHX2KDM1AMAOBMAOA | |
| SCHEMBL7375062 | 0.88 | KDM1A (0.46) | KMT2AEPHX2KDM1AMAOBMAOA | |
| SCHEMBL7367127 | 0.88 | ATM (0.51) | NPC1RAB9ASMN1; SMN2TAOK1MAPT | |
| SCHEMBL8638808 | 0.88 | ATM (0.51) | NPC1RAB9ASMN1; SMN2TAOK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773463-A | DECALCIFICATION OF BRAIN DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-06-30 | — | — | US | disclosed |