Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.41 |
| ▸ | BRD2 | P25440 | 2/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316267 | 0.92 | BRD4 (0.41) | BRD4BRD2BRD3ALDH1A1MAPT | |
| SCHEMBL8317477 | 0.84 | BRD4 (0.46) | BRD4BRD2BRD3ALDH1A1LMNA | |
| SCHEMBL8319665 | 0.84 | BRD4 (0.46) | BRD4BRD2BRD3ALDH1A1LMNA | |
| SCHEMBL8324403 | 0.83 | BRD4 (0.44) | BRD4BRD2BRD3ALDH1A1MAPT | |
| SCHEMBL8316425 | 0.83 | BRD4 (0.46) | BRD4BRD2BRD3ALDH1A1LMNA | |
| SCHEMBL8317053 | 0.82 | BRD4 (0.45) | BRD4BRD2BRD3 | |
| SCHEMBL8317879 | 0.79 | BRD4 (0.41) | BRD4BRD2BRD3ALDH1A1LMNA | |
| SCHEMBL8801054 | 0.79 | BRD4 (0.46) | BRD4BRD2BRD3ALDH1A1LMNA | |
| SCHEMBL8318916 | 0.79 | BRD4 (0.45) | BRD4BRD2BRD3LMNA | |
| SCHEMBL8317679 | 0.78 | BRD4 (0.47) | BRD4BRD2BRD3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807850-A | Therapeutic agent for osteoporosis and triazepine compound | JAPAN TOBACCO, INC. (JP) | 1998-09-15 | — | — | US | claimed |