Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999393 | 1.00 | POLB (0.51) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL14344759 | 0.82 | ATM (0.41) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11350774 | 0.82 | ATM (0.41) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11671625 | 0.82 | ATM (0.41) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL10932532 | 0.82 | KMT2A (0.50) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL10932521 | 0.82 | KMT2A (0.50) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL673023 | 0.82 | POLB (0.50) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11299302 | 0.80 | KMT2A (0.49) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL14975958 | 0.80 | KMT2A (0.49) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL14975956 | 0.80 | KMT2A (0.49) | POLBKMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622381-B1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORP (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-5698646-A | ANIONIC POLYMERIZATION OF BUTADIENE-STYRENE COPOLYMER USING LITHIUM COMPOUND AND CHELATE COMPOUND | BRIDGESTONE CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0451603-B1 | Elastomers and products having reduced hysteresis | BRIDGESTONE FIRESTONE INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0622381-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5354822-A | Endcapping the addition polymerization with a reaction product of an aldimines, a ketimines, a secondary amines and an organo lithium compound prior quenching | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-10-11 | — | — | US | disclosed |
| US-5268413-A | Blend of functionalized polymer and organolithium compound | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-12-07 | — | — | US | disclosed |
| US-5153159-A | ELASTOMERS AND PRODUCTS HAVING REDUCED HYSTERESIS | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0451603-A2 | Elastomers and products having reduced hysteresis | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |