SCHEMBL8636964

SCHEMBL8636964

CCCC(=O)Cc1ccc(OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.58
F2RL1 P55085 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.53
CTBP2 P56545 1/20 0.51
LMNA P02545 1/20 0.51
KMT2A Q03164 1/20 0.50
VNN1 O95497 1/20 0.50
ALDH1A1 P00352 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C19 P33261 1/20 0.49
USP2 O75604 1/20 0.49
TP53 P04637 1/20 0.49
KDM4E B2RXH2 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10743710 0.89 HTT (0.54) HTTF2RL1SMN1; SMN2CTBP2LMNA
SCHEMBL9234996 0.86 CNR1 (0.54) HTTF2RL1CYP3A4CYP2C19
SCHEMBL3628705 0.86 HTT (0.68) HTTF2RL1SMN1; SMN2CTBP2LMNA
SCHEMBL7153605 0.85 HTT (0.61) HTTF2RL1SMN1; SMN2CTBP2LMNA
SCHEMBL6936332 0.84 HTT (0.56) HTTF2RL1SMN1; SMN2CTBP2LMNA
SCHEMBL1915418 0.84 HTT (0.56) HTTF2RL1SMN1; SMN2CTBP2VNN1
SCHEMBL8623716 0.84 HTT (0.56) HTTF2RL1SMN1; SMN2CTBP2LMNA
SCHEMBL5152755 0.81 KMT2A (0.43) KMT2AALDH1A1POLB
SCHEMBL3175977 0.81 HTT (0.61) HTTF2RL1SMN1; SMN2CTBP2LMNA
SCHEMBL8966822 0.81 HTT (0.53) HTTF2RL1SMN1; SMN2CTBP2VNN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
EP-0516257-B1 Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same SCHERING AG (DE) 1998-08-05 EP disclosed
US-5470854-A Antiestrogens SCHERING AKTIENGESELLSCHAFT (DE) 1995-11-28 US disclosed
WO-1992021669-A1 2-PHENYLBENZO[B]FURANS AND THIOPHENES, METHODS OF PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1992-12-10 WO disclosed
EP-0516257-A1 Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same SCHERING AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed