SCHEMBL8637243

SCHEMBL8637243

CC(F)(C(F)F)C(F)(F)Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9473304 0.81
SCHEMBL10348915 0.80 TSHR (0.31) TSHR
SCHEMBL8637592 0.75
SCHEMBL8635791 0.75
SCHEMBL1994642 0.74
SCHEMBL23551933 0.72
SCHEMBL250468 0.72
SCHEMBL9167716 0.72
SCHEMBL16101318 0.70
SCHEMBL14724266 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705716-A COMPOUNDS FOR SOLVENTS AND BLOWING AGENTS ALLIEDSIGNAL INC. (US) 1998-01-06 US disclosed
EP-0641300-A1 HYDROCHLOROFLUOROCARBONS HAVING OH RATE CONSTANTS WHICH DO NOT CONTRIBUTE SUBSTANTIALLY TO OZONE DEPLETION AND GLOBAL WARMING AlliedSignal Inc. (US) 1995-03-08 EP disclosed
US-5316690-A Blowing agents or solvents ALLIED SIGNAL INC. (US) 1994-05-31 US disclosed
WO-1993004025-A1 HYDROCHLOROFLUOROCARBONS HAVING OH RATE CONSTANTS WHICH DO NOT CONTRIBUTE SUBSTANTIALLY TO OZONE DEPLETION AND GLOBAL WARMING ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed
US-5158617-A Method of cleaning using hydrochlorofluorocarbons having 3 to 5 carbon atoms ALLIED-SIGNAL INC. 1992-10-27 US disclosed
WO-1992016674-A2 A METHOD OF CLEANING USING HYDROCHLOROFLUOROCARBONS HAVING 3 TO 5 CARBON ATOMS ALLIED-SIGNAL INC. (US) 1992-10-01 WO disclosed