SCHEMBL8637375

SCHEMBL8637375

CC(C)N(C(C)C)C(C)(C#N)OPCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906823 0.83
SCHEMBL8637309 0.72
SCHEMBL28755749 0.72
SCHEMBL6854962 0.69
SCHEMBL6536804 0.68
SCHEMBL8840679 0.68
SCHEMBL10590963 0.64
SCHEMBL8883216 0.63
SCHEMBL8191873 0.60
SCHEMBL8068584 0.58 TSHR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684954-B1 NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME WALLONE REGION (BE) 1998-07-22 EP claimed
EP-0684954-A1 NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME LA REGION WALLONNE (BE) 1995-12-06 EP claimed
WO-1994019364-A2 NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME LA REGION WALLONNE (BE) 1994-09-01 WO claimed
US-5218102-A Easily synthesized, hybridize well with target sequences IMPROBIO (BE) 1993-06-08 US claimed
EP-0684954-A1 NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME LA REGION WALLONNE (BE) 1995-12-06 EP disclosed
WO-1994019364-A2 NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME LA REGION WALLONNE (BE) 1994-09-01 WO disclosed
US-5218102-A Easily synthesized, hybridize well with target sequences IMPROBIO (BE) 1993-06-08 US disclosed