SCHEMBL8637488 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	13/20	0.39

▸	FNTB	P49356	13/20	0.39

▸	PGGT1B	P53609	10/20	0.38

▸	CYP11B1	P15538	2/20	0.37

▸	CYP11B2	P19099	2/20	0.37

▸	KCNH2	Q12809	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	GAA	P10253	1/20	0.35

▸	MAPT	P10636	1/20	0.35

▸	HTT	P42858	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8637483	1.00	FNTA (0.39)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8634544	0.95	FNTA (0.38)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8634542	0.95	FNTA (0.38)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8498759	0.92	FNTA (0.42)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8501475	0.91	FNTA (0.42)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8491433	0.90	FNTA (0.39)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8489468	0.88	FNTA (0.39)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8489464	0.88	FNTA (0.39)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8494065	0.87	FNTA (0.39)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8500009	0.86	FNTA (0.39)	FNTAFNTBPGGT1BCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999012912-A1	THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH	YUHAN CORPORATION (KR)	1999-03-18	—	—	WO	disclosed