Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SAT1 | P21673 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637561 | 1.00 | KDM1A (0.78) | KDM1ACYP2C19MEN1GLAKMT2A | |
| Hydrochloric Acid SCHEMBL8638454 | 0.98 | KDM1A (0.79) | KDM1ACYP2C19MEN1GLAKMT2A | |
| Hydrochloric Acid SCHEMBL8638451 | 0.98 | KDM1A (0.79) | KDM1ACYP2C19MEN1GLAKMT2A | |
| SCHEMBL5802301 | 0.91 | KDM1A (0.62) | KDM1ACYP2C19MEN1GLAKMT2A | |
| Cgc-11047 SCHEMBL2360444 | 0.89 | KDM1A (1.00) | KDM1ACYP2C19MEN1GLAKMT2A | |
| Cgc-11047 SCHEMBL2359734 | 0.89 | KDM1A (1.00) | KDM1ACYP2C19MEN1GLAKMT2A | |
| Cgc-11047 SCHEMBL2359741 | 0.89 | KDM1A (1.00) | KDM1ACYP2C19MEN1GLAKMT2A | |
| SCHEMBL8638098 | 0.89 | KDM1A (0.56) | KDM1AKMT2ATSHRCNR1CNR2 | |
| SCHEMBL8638101 | 0.89 | KDM1A (0.56) | KDM1AKMT2ATSHRCNR1CNR2 | |
| SCHEMBL22756216 | 0.86 | KDM1A (0.67) | KDM1ACYP2C19MEN1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | claimed |
| EP-0686143-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | Novartis AG (CH) | 1995-12-13 | — | — | EP | claimed |
| WO-1995018091-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | claimed |