Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MMP1 | P03956 | 5/20 | 0.60 |
| ▸ | MMP2 | P08253 | 5/20 | 0.60 |
| ▸ | MMP9 | P14780 | 5/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638075 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8640120 | 0.88 | SMN1; SMN2 (0.79) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8640127 | 0.88 | SMN1; SMN2 (0.79) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2781343 | 0.87 | MEN1 (0.78) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2781340 | 0.87 | MEN1 (0.78) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8641819 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8641811 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8638865 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8638857 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13675867 | 0.85 | TNIK (1.00) | SMN1; SMN2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |